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Virologica Sinica is an academic journal which aims at presenting the cutting-edge basic and applied research on viruses all over the world. The journal publishes peer-reviewed original research articles and reviews, as well as commentaries and letters to the editor, to encompass the latest developments in all branches of virology, including research on animal, plant and microbe viruses. The journal welcomes articles on virus discovery, viral pathogenesis...   (read more)
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ISSN: 1674-0769
EISSN: 1995-820X
CN: 42-1760/Q
2017 Impact Factor 2.415*
*2017 Journal Citation Reports
Editorial
The Society for Invertebrate Pathology (SIP) is foremost in the world covering all aspects of related research in insect virology, bacteriology, mycology, parasitology and microbial control. The SIP has a wide scientific appeal with members from many countries spanning every continent in the ..., Abstract
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Review
Nipah virus (NiV), a zoonotic paramyxovirus belonging to the genus Henipavirus, is classified as a Biosafety Level-4 pathogen based on its high pathogenicity in humans and the lack of available vaccines or therapeutics. Since its initial emergence in 1998 in Malaysia, this virus has become ..., Abstract
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Research Article
Seneca Valley virus (SVV), a newly determined etiological agent of vesicular disease in swine, causes porcine idiopathic disease and occasional acute death in piglets. Recently, an increased number of SVV infection cases have been reported in the United States (US) and China, resulting in ..., Abstract
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Research Article
Rasmussen's encephalitis (RE) is a rare pediatric neurological disorder, and the exact etiology is not clear. Viral infection may be involved in the pathogenesis of RE, but conflicting results have reported. In this study, we evaluated the expression of both Epstein-Barr virus (EBV) and human ..., Abstract
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Research Article
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic pathogen capable of causing severe respiratory disease in humans. Although dromedary camels are considered as a major reservoir host, the MERS-CoV infection dynamics in camels are not fully understood. Through surveillance in ..., Abstract
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Research Article
Histone deacetylase (HDAC) inhibitors show clinical promise for the treatment of cancers, including hepatocellular carcinoma (HCC). In this study, we investigated the effect of HDAC inhibitor treatment on hepatitis C virus (HCV) replication in Huh7 human liver cells and in a mouse model of HCV ..., Abstract
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Research Article
Porcine reproductive and respiratory syndrome virus (PRRSV) is a member within the family Arteriviridae of the order Nidovirales. Replication of this positive-stranded RNA virus within the host cell involves expression of viral replicase proteins encoded by two ORFs, namely ORF1a ..., Abstract
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Research Article
Cyclophilin A (CypA) is a peptidyl-prolyl cis/trans isomerase that interacts with the matrix protein (M1) of influenza A virus (IAV) and restricts virus replication by regulating the ubiquitin–proteasome-mediated degradation of M1. However, the mechanism by which CypA regulates M1 ..., Abstract
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Letter
Marine mammals are widely distributed and can be found almost in all coastal waters and coastlines around the world. The interface areas between marine and terrestrial environments provide natural habitats for aquatic and semiaquatic mammals as well as for reservoir species of avian influenza ..., Abstract
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Letter
Middle East respiratory syndrome coronavirus (MERS-CoV) is a major health concern to the general population, with no available licensed therapeutic or vaccine. Virus-like particles (VLPs) comprise viral structural proteins, which represent a safe and highly immunogenic vaccine delivery platform ..., Abstract
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Perspective
Recent study by Joel Dudley and colleagues published in Neuron on July 11, demonstrated that both HHV-6A and HHV-7 could be key causal contributors to Alzheimer’s disease (AD). However, among various biological and technical issues, we review how complicate to demonstrate the link of HHV-6A ..., Abstract
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Perspective
Hepatitis B virus (HBV) infection remains a great public health problem worldwide. Here, we discuss the rationality and possibility of cellular inhibitor of apoptosis proteins (cIAPs) as a therapeutic target for HBV functional cure, and introduce the ongoing Phase I clinical study of cIAPs ..., Abstract
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