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Virologica Sinica, 28 (1) : 1-2, 2013
News & Views
How the Key Finds its Door-Identification of HBV Receptor
Skate Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, China
 Correspondence: wangyun@wh.iov.cn
HBV is the predominant pathogen associated with hepatitis cases in China. Although the HBV replication mechanism has been extensively documented in recent years, the virus entry mechanism remains elusive; in particular, the HBV receptor has yet to be identified. Recently, a research team led by Dr. Wenhui Li finally identified Sodium taurocholate cotransporting polypeptide (NTCP) as the receptor for HBV infection of hepatocytes (Yan H, et al., 2012). This review highlights their research strategy, as well as the significance of the identification of the HBV receptor.
Key Words: HBV;  Receptor;  Sodium taurocholate
Received: 31 Dec 2012  Accepted: 28 Dec 2012  Published online: 1 Feb 2013
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