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Virologica Sinica, 32 (3) : 245, 2017
Letter
Retromer localizes to autophagosomes during HCV replication
1. MOH Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100176, China
2. Department of Emergency, 171st Hospital of PLA, Jiujiang 332000, China
 Correspondence: armzhang@hotmail.com;keyouyang001@163.com
(2153.77KB)  
Abstract
In summary, we propose a model for the role of retromer in HCV replication. Upon HCV infection, retromer may provide double-membrane autophagosomal membranes for HCV replication. Our studies suggested a novel link between retromer and autophagy in HCV replication, which may provide new therapeutic targets for antiviral therapy.
Key Words:
Received: 13 Apr 2017  Accepted: 13 Apr 2017  Published online: 13 Apr 2017
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