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Virologica Sinica, 32 (3) : 257, 2017
CD95-CD95L interaction mediates the growth control of MHV68 immortalized B cells by cytotoxic T cells
1. School of Life Science, Shanghai University, Shanghai 200444 China
2. Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, China
 Correspondence: xzliang@ips.ac.cn
In conclusion, our current data demonstrate that MHV68-immortalized SL-1 cells can be recognized and controlled by specific cytotoxic T cells through CD95/CD95L-mediated apoptosis. This is in agreement with that CD4 T cells control the growth of EBV-infected cells through CD95/CD95L-mediated apoptosis, which suggests that the growth control of gammaherpesvirus-associated lymphoma cells by cytotoxic T cell shares conserved mechanism.
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Received: 15 May 2017  Accepted: 15 May 2017  Published online: 15 May 2017
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