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Virologica Sinica, 33 (4) : 378, 2018
Serological Cross Reactivity between Zika and Dengue Viruses in Experimentally Infected Monkeys
Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore
 Correspondence: linfa.wang@duke-nus.edu.sg;danielle.anderson@duke-nus.edu.sg
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In the absence of serum panels from individuals with absolute defined infection status, sera from experimentally infected monkeys were generated to cover all four infection scenarios with Zika or dengue virus alone as well as Zika infection followed by dengue and dengue infection followed by Zika. Our data indicated that no currently available single assay platform is sufficiently specific to serologically determine Zika positivity in the presence of prior exposure to dengue and vice versa.
Received: 11 Jun 2018  Accepted: 8 Sep 2018  Published online: 28 Aug 2018
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