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Virologica Sinica, 34 (1) : 111, 2019
Genetic Analysis of an Emerging GII.P2–GII.2 Norovirus Associated with a 2016 Outbreak of Acute Gastroenteritis in China
1. National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China

2. Graduate School, Peking Union Medical College, Beijing 100730, China

3. Fengtai District Center for Disease Control and Prevention, Beijing 100071, China
 Correspondence: zhaojund@126.com
(399.85KB)  (199.52KB)  
In the 2016–2017 winter season, a GII.P16-GII.2 norovirus that had previously been rarely detected was responsible for a majority of the outbreaks of gastroenteritis in China and other countries. Another GII.2 virus, GII.P2-GII.2, had been rarely reported as a cause of gastroenteritis outbreaks since 2010. In this study, an emerging GII.P2-GII.2 variant was identified to be involved in an outbreak in the Fengtai District, Beijing, China in December 2016. Sequence and phylogenetic analyses indicated that this GII.2 strain is a novel recombinant virus that evolved in the 2011–2012 season from the 2011–2012 GII.P16-GII.2 and 2011 GII.P2-GII.2 strains. Phylogenetic analyses indicated that this GII.2 strain appears to have been introduced to China from Russia, where it was first detected as being involved in sporadic gastroenteritis in July 2016. Sequence analyses revealed that no significant mutation both in the VP1 and polymerase proteins was observed in this virus. Continuous surveillance of the epidemiology of this norovirus is necessary to further understand its evolution and significance in public health.
Received: 28 Sep 2018  Accepted: 19 Dec 2018  Published online: 6 Feb 2019
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