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Author [胡勤学] article list of Virologica Sinica
Skin-resident dendritic cells (DCs) likely encounter incoming viruses in the first place, and their migration to lymph nodes following virus capture may promote viral replication. However, the molecular mechanisms underlying these processes remain unclear. In the present study, we found that ..., Abstract
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The occurrence of massive CD4+ T cell depletion is one of the most prominent characteristics of human immunodeficiency virus type 1 (HIV-1) infection during acute phase, resulting in unrestorable destruction to the immune system. The infected host undergoes an asymptomatic period ..., Abstract

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Studies of the mechanism of HIV entry and transmission have identified multiple new targets for drug development. A range of inhibitors have demonstrated potent antiretroviral activity by interfering with CD4-gp120 interaction, coreceptor binding or viral-cell fusion in preclinical and clinical ..., Abstract
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Abstract:ChemokiRe receptor CCR5 and CXCR4 are principal coreceptors for HIV Blockage of
Human immunodeficiecy virus(HIV)infection can be achieved by engaging CCR5 and CXCR4 with their
natural ligands. man herpesvirus 8 encodes three chemokines: vM IP1.vMIP2 and vM IP3.vM Ⅱ’2
has ..., Abstract
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