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Author [Mengji Lu] article list of Virologica Sinica
The role of microRNAs in hepatocyte metabolism and hepatitis B virus replication
Wanyu Deng, Mengji Lu
Though efficient vaccines against hepatitis B virus (HBV) and antiviral therapies are available,chronic HBV infection is still a global health problem. The process of HBV infection and HBV life cycle are extensively studied in last decades, however, the mechanisms of HBV-induced alterations of host ..., Abstract
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2016 Vol. 31 (6): 472
CRISPR/Cas9-based tools for targeted genome editing and replication control of HBV
Cheng Peng, Mengji Lu, Dongliang Yang
Hepatitis B virus (HBV) infection remains a major global health problem because current therapies rarely eliminate HBV infections to achieve a complete cure. A different treatment paradigm to effectively clear HBV infection and eradicate latent viral reservoirs is urgently required. In ..., Abstract
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2015 Vol. 30 (5): 317-325
New therapeutic vaccination strategies for the treatment of chronic hepatitis B
Jia Liu, Anna Kosinska, Mengji Lu, Michael Roggendorf
Chronic hepatitis B virus (CHB) is currently treated with either interferon-based or nucleot(s)ide-based antiviral therapies. However, treatment with pegylated interferon alpha results in a durable antiviral response in only about 30% patients and is associated with side effects. Most patients ..., Abstract
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2014 Vol. 29 (1): 10-16
Interaction of viruses with immune cells and immunomodulation in chronic viral infections
Mengji Lu, Yumei Wen
When you closely read the papers in this issue, you may find those researches are commonly founded by a so-called TRR60 program. The Transregional Collaboration Re-search Project (TRR) is a highly ranked program of German Research Foundation (DFG) to support the scientific competence with a strong ..., Abstract
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2014 Vol. 29 (1): 1-2
A Case of Hepatitis B Reactivation in an Anti-HBs Positive, Anti-HBc Positive non-Hodgkin’s Lymphoma Patient
Chunchen Wu, Hui Shi, Mengji Lu, Yang Xu, Xinwen Chen
Abstract
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2013 Vol. 28 (1): 49-52
A Case of Hepatitis B Reactivation due to the Hepatitis B Virus Escape Mutant in a Patient undergoing Chemotherapy
Chunchen Wu, Hui Shi, Yun Wang, Mengji Lu, Yang Xu, Xinwen Chen
A 62-year-old man had chronic hepatitis B virus (HBV) infection and was diagnosed with liver cirrhosis. At the time of diagnosis the patient’s virologic markers were positive for hepatitis B surface antigen (HBsAg), antibody to hepatitis B e antigen (anti-HBe) and antibody to hepatitis B core ..., Abstract
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2012 Vol. 27 (6): 369
Recent Advances in Research on Hepadnaviral Infection in the Woodchuck Model*
Ina Schulte, E-juan ZHANG, Zhong-ji MENG, Rong-juan PEI, Mengji LU, Michael Roggendorf
The woodchuck model is an excellent animal model to study hepadnaviral infection. The new progresses in this model made possible to examine the T-cell mediated immune responses in acute and chronic hepadnaviral infection. Recently, a new assay for cytotoxic T-cells based on detection of CD107 was ..., Abstract
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2008 Vol. 23 (2): 107-115
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