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Author [Qinxue Hu] article list of Virologica Sinica
Skin-resident dendritic cells (DCs) likely encounter incoming viruses in the first place,and their migration to lymph nodes following virus capture may promote viral replication.However,the molecular mechanisms underlying these processes remain unclear.In the present study,we found that compared to ..., Abstract
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HIV-1 envelope glycoprotein is reported to interact with α4β7, an integrin mediating the homing of lymphocytes to gut-associated lymphoid tissue, but the signifi cance of α4β7 in HIV-1 infection remains controversial. Here, using HIV-1 strain BaL, the ..., Abstract
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Studies of the mechanism of HIV entry and transmission have identified multiple new targets for drug development. A range of inhibitors have demonstrated potent antiretroviral activity by interfering with CD4-gp120 interaction, coreceptor binding or viral-cell fusion in preclinical and clinical ..., Abstract
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