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Author [Rongjuan Pei] article list of Virologica Sinica
Hepatitis C virus-induced prion protein expression facilitates hepatitis C virus replication
Huixia Zhang, Shanshan Gao, Rongjuan Pei, Xinwen Chen, Chaoyang Li
Hepatitis C virus (HCV) infects approximately 180 million people worldwide. Significant progress has been made since the establishment of in vitro HCV infection models in cells. However, the replication of HCV is complex and not completely understood. Here, we found that the expression of ..., Abstract
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2017 Vol. 32 (6): 503
Productive HBV infection of well-differentiated, hNTCP-expressing human hepatoma-derived (Huh7) cells
Ming Zhou, Kaitao Zhao, Yongxuan Yao, Yifei Yuan, Rongjuan Pei, Yun Wang, Jizheng Chen, Xue Hu, Yuan Zhou, Xinwen Chen, Chunchen Wu
Feasible and effective cell models for hepatitis B virus (HBV) infection are required for investigating the complete lifecycle of this virus, including the early steps of viral entry. Resistance to dimethyl sulfoxide/polyethylene glycol (DMSO/PEG), hNTCP expression, and a differentiated state are ..., Abstract
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2017 Vol. 32 (6): 465
Construction of a chimeric hepatitis C virus replicon based on a strain isolated from a chronic hepatitis C patient
Huang Cao, Wandi Zhu, Qingxia Han, Rongjuan Pei, Xinwen Chen
Subgenomic replicons of hepatitis C virus (HCV) have been widely used for studying HCV replication. Here, we report a new subgenomic replicon based on a strain isolated from a chronically infected patient. The coding sequence of HCV was recovered from a Chinese chronic hepatitis C patient ..., Abstract
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2014 Vol. 29 (1): 61-70
Different Responses of Two Highly Permissive Cell Lines Upon HCV Infection
Honghe Chen, Rongjuan Pei, Xinwen Chen
The construction of the first infectious clone JFH-1 speeds up the research on hepatitis C virus (HCV). However, Huh7 cell line was the only highly permissive cell line for HCV infection and only a few clones were fully permissive. In this study, two different fully permissive clones of Huh7 cells ..., Abstract
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2013 Vol. 28 (4): 202-208
Regulation of Hepatitis C Virus Replication and Gene Expression by the MAPK-ERK Pathway
Rongjuan Pei, Xiaoyong Zhang, Song Xu, Zhongji Meng, Michael Roggendorf
The mitogen activated protein kinases-extracellular signal regulated kinases (MAPK-ERK) pathway is involved in regulation of multiple cellular processes including the cell cycle. In the present study using a Huh7 cell line Con1 with an HCV replicon, we have shown that the MAPK-ERK pathway plays a ..., Abstract
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2012 Vol. 27 (5): 278
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