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Author [Rongjuan Pei] article list of Virologica Sinica
Feasible and effective cell models for hepatitis B virus (HBV) infection are required for investigating the complete lifecycle of this virus,including the early steps of viral entry.Resistance to dimethyl sulfoxide/polyethylene glycol (DMSO/PEG),hNTCP expression,and a differentiated state are the ..., Abstract
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Hepatitis C virus (HCV) infects approximately 180 million people worldwide.Significant progress has been made since the establishment of in vitro HCV infection models in cells.However,the replication of HCV is complex and not completely understood.Here,we found that the expression of host ..., Abstract
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Subgenomic replicons of hepatitis C virus (HCV) have been widely used for studying HCV replication. Here, we report a new subgenomic replicon based on a strain isolated from a chronically infected patient. The coding sequence of HCV was recovered from a Chinese chronic hepatitis C patient ..., Abstract
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The construction of the first infectious clone JFH-1 speeds up the research on hepatitis C virus (HCV). However, Huh7 cell line was the only highly permissive cell line for HCV infection and only a few clones were fully permissive. In this study, two different fully permissive clones of Huh7 cells ..., Abstract
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The mitogen activated protein kinases-extracellular signal regulated kinases (MAPK-ERK) pathway is involved in regulation of multiple cellular processes including the cell cycle. In the present study using a Huh7 cell line Con1 with an HCV replicon, we have shown that the MAPK-ERK pathway plays a ..., Abstract
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