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Author [Wei Wang] article list of Virologica Sinica
Mammarenaviruses, including lethal pathogens such as Lassa virus and Junín virus, can cause severe hemorrhagic fever in humans. Entry is a key step for virus infection, which starts with binding of the envelope glycoprotein (GP) to receptors on target cells and subsequent fusion of the virus ..., Abstract
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In the present study, we reported the full genome sequence of a novel bacteriophage, designated as IME- 16, via screening pathogens from a throat swab obtained from a patient with an unexplained fever. The viral DNA and RNA were extracted using a High Pure Viral RNA Kit (Roche, Germany). ..., Abstract
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Torque teno virus (TTV) has been found to be prevalent world-wide in healthy populations and in patients with various diseases, but its etiological role has not yet been determined. Using highthroughput unbiased sequencing to screen for viruses in the serum of a patient with persistent high fever ..., Abstract
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Infection by foot-and-mouth disease virus (FMDV) is triggered by the acidic pH in endosomes after virus uptake by receptor-mediated endocytosis. However, dissociation of the FMDV 146S particle in mildly acidic conditions renders inactivated foot-and-mouth disease (FMD) vaccines much less effective. ..., Abstract
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SARS-CoV is a newly discovery pathogen causing severe acute respiratory syndrome, S protein play an important rule in the adsorption and penetration of SARS-CoV into the cell by interaction with ACE2 receptor. To determinant the functional motif of S protein involved in the interaction with ACE2 ..., Abstract
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