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Author [Ying Zhang] article list of Virologica Sinica
We previously constructed a herpes simplex virus 1(HSV-1) UL7 mutant virus (M1) and showed that a partial deletion mutation of the UL7 gene led to a lower proliferative rate and an attenuated phenotype.Using the M1 mutant,we further modified the UL41 gene,which encodes another ..., Abstract
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Since April 2010, an outbreak of a new disease has elicited symptoms of high fever, loss of appetite, and reduction in egg production in layer ducks in eastern China; this phenomenon has now spread throughout China (Cao et al., 2011; Su et al., 2011). The causative agent of the disease was ..., Abstract
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Herpes simplex virus-1 (HSV-1) is a major pathogen that causes various central nervous system (CNS) diseases, including herpes simplex encephalitis and meningitis. According to recent studies, PNKP significantly affects the proliferation of HSV-1 in astrocytes. Here, we used viral proliferation ..., Abstract
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In light of the scarcity of reports on the interaction between HSV-1 nucleocapsid protein UL25 and its host cell proteins, the purpose of this study is to use yeast two-hybrid screening to search for cellular proteins that can interact with the UL25 protein. C9orf69, a protein of unknown function ..., Abstract
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An interaction between the HSV-1 UL25 capsid protein and cellular microtubule-associated protein was found using a yeast two-hybrid screen and β–D-galactosidase activity assays. Immunofluorescence microscopy of the UL25 protein demonstrated its co-localization with cellular microtubule-associated ..., Abstract
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