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E-First publication of Virologica Sinica
A common reason for drug failure during long-term treatment of chronic hepatitis B with nucleot (s) ide analogues (NUCs) is the emergence of drug resistance (Das et al.,2001).Most primary NUCs-resistant mutations identified in clinical samples have been limited to a minority of amino acids (usually ..., Abstract
Free PDF (1610.49KB)  |  Springerlink  |  ESM  |  23 Mar 2017  |  DOI:10.1007/s12250-016-3932-0
Rasmussen's encephalitis (RE) is a rare and severe progressive epileptic syndrome with unknown etiology.Infection by viruses,including human cytomegalovirus (HCMV),has been speculated to be a potential trigger for RE.However,no viral antigens have been detected in the brains of patients with ..., Abstract
Free PDF (1984.34KB)  |  16 Mar 2017
Natural killer (NK) cell is a key component of innate immunity and plays an important role in host defense against virus infection by directly destroying infected cells. Influenza is a respiratory disease transmitted in the early phase of virus infection. Evasion of host innate immunity including ..., Abstract
Free PDF (794.41KB)  |  Springerlink  |  23 Feb 2017  |  DOI:10.1007/s12250-016-3918-y
Noroviruses are the leading cause of acute gastroenteritis in humans. Real-time reverse transcription-polymerase chain reaction (real-time RT-PCR) is a promising molecular method for the detection of noroviruses. In this study, the performance of three TaqMan real-time RT-PCR assays was assessed ..., Abstract
Free PDF (392.41KB)  |  Springerlink  |  20 Feb 2017  |  DOI:10.1007/s12250-016-3863-9
The genus Orbivirus, within the family Reoviridae, includes 22 virus species (King et al., 2011). They are distributed globally, but are particularly prevalent in Europe, Asia, and Africa. In addition, they can be transmitted by ticks or other hematophagous insect vectors,including ..., Abstract
Free PDF (1302.75KB)  |  Springerlink  |  ESM  |  5 Jan 2017  |  DOI:10.1007/s12250-016-3886-2
Rabies, a zoonotic disease, causes > 55,000 human deaths globally and results in at least 500 million dollars in losses every year. The currently available rabies vaccines are mainly inactivated and attenuated vaccines, which have been linked with clinical diseases in animals. Thus, a ..., Abstract
Free PDF (1729.59KB)  |  Springerlink  |  7 Apr 2016  |  DOI:10.1007/s12250-016-3734-4
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