E-First publication of Virologica Sinica
Noroviruses are the leading cause of acute gastroenteritis in humans. Real-time reverse transcription-polymerase chain reaction (real-time RT-PCR) is a promising molecular method for the detection of noroviruses. In this study, the performance of three TaqMan real-time RT-PCR assays was assessed ..., Abstract
Free PDF (392.41KB)  |  Springerlink  |  20 Feb 2017  |  DOI:10.1007/s12250-016-3863-9
Hantaviruses belong to the family Bunyaviridae and cause hemorrhagic fever with renal syndrome (HFRS) in humans. β3 integrins, including αVβ3 and αIIbβ3 integrins, act as receptors on endothelial cells and play key roles in cellular ..., Abstract
Free PDF (631.51KB)  |  Springerlink  |  10 Feb 2017  |  DOI:10.1007/s12250-016-3888-0
Dengue virus (DENV) belongs to the genus Flavivirus of the family Flaviviridae and it is primarily transmitted via Aedes aegypti and Aedes albopictus mosquitoes. The life cycle of DENV includes attachment, endocytosis, protein translation, RNA synthesis, assembly ..., Abstract
Free PDF (287.22KB)  |  Springerlink  |  24 Jan 2017  |  DOI:10.1007/s12250-016-3902-6
The dengue virus (DENV) is a vital global public health issue. The 2014 dengue epidemic in Guangzhou, China, caused approximately 40,000 cases of infection and five deaths. We carried out a comprehensive investigation aimed at identifying the transmission sources in this dengue epidemic. To analyze ..., Abstract
Free PDF (1727.08KB)  |  Springerlink  |  23 Jan 2017  |  DOI:10.1007/s12250-016-3872-8
Hantaviruses are comprised of tri-segmented negative sense single-stranded RNA, and are members of the Bunyaviridae family. Hantaviruses are distributed worldwide and are important zoonotic pathogens that can have severe adverse effects in humans. They are naturally maintained in specific ..., Abstract
Free PDF (2381.34KB)  |  Springerlink  |  23 Jan 2017  |  DOI:10.1007/s12250-016-3899-x
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a newly identified viral pathogen of the genus Phlebovirus in the family Bunyaviridae (Sun et al., 2012). SFTSV was first identified from patient serum samples in China (Li et al., 2013; Ning et al., 2015)., Abstract
Free PDF (5960.21KB)  |  Springerlink  |  ESM  |  23 Jan 2017  |  DOI:10.1007/s12250-016-3928-9
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a globe-shaped virus covered by a dense icosahedral array of glycoproteins Gn/Gc that mediate the attachment of the virus to host cells and the fusion of viral and cellular membranes. Several membrane factors are involved in virus entry ..., Abstract
Free PDF (3059.10KB)  |  Springerlink  |  5 Jan 2017  |  DOI:10.1007/s12250-016-3858-6
Dengue virus (DENV) is a mosquito-borne virus belonging to the Flaviviridae family. There are 4 serotypes of DENV that cause human disease through transmission by mosquito vectors. DENV infection results in a broad spectrum of clinical symptoms, ranging from mild fever to dengue hemorrhagic fever ..., Abstract
Free PDF (578.96KB)  |  Springerlink  |  5 Jan 2017  |  DOI:10.1007/s12250-016-3855-9
Ebolaviruses are highly dangerous pathogens exhibiting extreme virulence in humans and nonhuman primates. The majority of ebolavirus species, most notably Zaire ebolavirus, can cause Ebola virus disease (EVD), formerly known as Ebola hemorrhagic fever, in humans. EVD is associated with ..., Abstract
Free PDF (9943.91KB)  |  Springerlink  |  5 Jan 2017  |  DOI:10.1007/s12250-016-3850-1
The genus Orbivirus, within the family Reoviridae, includes 22 virus species (King et al., 2011). They are distributed globally, but are particularly prevalent in Europe, Asia, and Africa. In addition, they can be transmitted by ticks or other hematophagous insect vectors,including ..., Abstract
Free PDF (1302.75KB)  |  Springerlink  |  ESM  |  5 Jan 2017  |  DOI:10.1007/s12250-016-3886-2
Rabies, a zoonotic disease, causes > 55,000 human deaths globally and results in at least 500 million dollars in losses every year. The currently available rabies vaccines are mainly inactivated and attenuated vaccines, which have been linked with clinical diseases in animals. Thus, a ..., Abstract
Free PDF (1729.59KB)  |  Springerlink  |  7 Apr 2016  |  DOI:10.1007/s12250-016-3734-4
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