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Just Accepted Manuscripts Virologica Sinica
Dengue virus (DENV) and Zika virus (ZIKV) have spread throughout many countries in the developing world and infect millions of people every year, causing severe harm to human health and the economy. Unfortunately, there are few effective vaccines and therapies available against these viruses. ..., Abstract
Free PDF (686.33KB)  |  Springerlink  |  21 Nov 2018  |  DOI:10.1007/s12250-018-0068-4
Japanese encephalitis virus (JEV) is a mosquito-borne virus and the major cause of viral encephalitis in Asia. NS1', a 52-amino acid C-terminal extension of NS1, is generated with a -1 programmed ribosomal frameshift and is only present in members of the Japanese encephalitis serogroup of ..., Abstract
Free PDF (692.07KB)  |  Springerlink  |  21 Nov 2018  |  DOI:10.1007/s12250-018-0067-5
The major difficulties of human papillomavirus (HPV) treatment are its persistence and recurrence. The HPV E7 oncoprotein-loaded dendritic cells have been evaluated as cellular vaccine in previous reports. Plasmacytoid dendritic cells (pDCs) play an essential role of connecting the innate immune ..., Abstract
Free PDF (1570.00KB)  |  Springerlink  |  21 Nov 2018  |  DOI:10.1007/s12250-018-0069-3
Cellular microRNAs (miRNAs) have been shown to modulate HCV infection via directly acting on the viral genome or indirectly through targeting the virus-associated host factors. Recently we generated a comprehensive map of HCV– miRNA interactions through genome-wide miRNA functional screens and ..., Abstract
Free PDF (3052.11KB)  |  Springerlink  |  ESM  |  19 Nov 2018  |  DOI:10.1007/s12250-018-0055-9
Since the publication of the DRiP (defective ribosomal product) hypothesis in 1996, numerous studies have addressed the contribution of DRiPs to generating viral antigenic peptides for CD8+ T cell immunosurveillance. Here, we review studies characterizing the generation of antigenic ..., Abstract
Free PDF (401.14KB)  |  Springerlink  |  19 Nov 2018  |  DOI:10.1007/s12250-018-0061-y
2',3'-dideoxyguanosine (DoG) has been demonstrated to inhibit duck hepatitis B virus (DHBV) replication in vivo in a duck model of HBV infection. In the current study, the in vitro antiviral effects of DoG on human and animal hepadnaviruses were investigated. Our results showed that DoG effectively ..., Abstract
Free PDF (749.04KB)  |  Springerlink  |  29 Oct 2018  |  DOI:10.1007/s12250-018-0065-7
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