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Articles list with the same subject [Tumor] of Virologica Sinica
Oncolytic measles virus (OMV) is a promising antitumor agent. However, the presence of anti-measles neutralizing antibodies (NAbs) against the hemagglutinin (H) protein of OMV is a major barrier to the therapeutic application of OMV in clinical practice. In order to overcome this challenge ..., Abstract
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Mechanism of oncolysis of Newcastle disease virus (NDV) CN strain is studied in vitro in five carcinoma cells including HEP3B, T24, A549 and Hela cells, The pseudopods of the infected cells were retracted after 16h infected with 16HU/mL CN strain, the cells changed round and lost adhesion, the ..., Abstract
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In order to investigate the detection methods and gene structure of SV40 ST-ag and LT—ag—
C in peripheral blood mononuclear cells (PBMC) and kidney cells from different Macaque monkeys,
using PCR, 4 positive templates were obtained firstly, then 4 ST—ag gene fragments and 4 ..., Abstract
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The present is aimed at identifying the activation of TRAFs in nasopharyngeal carcinoma
(NPC)ill"oitro The differentia1 expression of TRAF2、TRAF3 was not detected in RNA and protein
1evel,whereas the expression of TRAF1 in HNE2一LM P1 eel1 1ines was much more abundant than that
in ..., Abstract
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Objective\ To study the relationship between the changes of Interleukin and Receptor in serum of patients with chronic hepatitis B (CHB) before and after Interferon α (IFN α) treatment and expression of HBV marker. Methods: Enzyme liked immunosorbent assay (ELISA) were performed in 25 ..., Abstract
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The production of tumor necrosis factor alpha(TNF-a)induced by human herpesvims
7(HHV一7)G1asgow strain and Nanjing loca1 strain YY5 and HHV一6 GS strain in umbilica1 cord
and pheripheraI blood mononuclear cells cultures was studied by means of biologicaI activity assay.
It ..., Abstract
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E1A gene of adenovirus is an apoptosis-inducing gene and E1B gene of adenovirus is anapoptosis-inhibiting gene. The former one was cloned into adenovirus transfer vector pCA13 under the control of HCMV IE1 promoter, which resulted into transfer vector pCAE1A. PlasmidpCAE1A and pBHG11, which ..., Abstract
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here are high levels of TNF-α in the supernatants of lymphocyte culture infected with HHV-6 GS strain and the Nanjing loeal strains.TNF-α was detected by two methods:biological ac-tivity assay using L929 cells and ELISA.HHV-6 can induce TNF-α with in 24 h,maximal re-lease of TNF-α occurred ..., Abstract
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This paper reports the protective effect of human rTNF-α and Human IFN-α on HEL andNEP-2 cell cultures infected by viruses in vitro,That is,before virus challenge,the treatment ofcell cultures in comparison with TNF-αand IFN-α may result in the inhibition of virus inducedcytopattiy.The ..., Abstract
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We successfully established a system in vitro that HSV-Ⅰ infected human tonsillar lymphocytes. Tonsillar lymphocytes prestimulated with PWM(10μg/ml) were infected by living HSV-Ⅰ, so as to their proliferation and IgG synthesis were abated significantly(P<0.005).In the supernatants, the infective ..., Abstract
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