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Articles list with the same subject [receptor] of Virologica Sinica
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a globe-shaped virus covered by a dense icosahedral array of glycoproteins Gn/Gc that mediate the attachment of the virus to host cells and the fusion of viral and cellular membranes. Several membrane factors are involved in virus entry ..., Abstract
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Avian infectious bronchitis virus (IBV) is a Gammacoronavirus in the family Coronaviridae and causes highly contagious respiratory disease in chickens. Innate immunity plays significant roles in host defense against IBV. Here, we explored the interaction between IBV and the host innate immune ..., Abstract
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The surface glycoproteins of coronaviruses play an important role in receptor binding and cell entry. Different coronaviruses interact with their specific receptors to enter host cells. Lentiviruses pseudotyped with their spike proteins (S) were compared to analyze the entry efficiency of ..., Abstract
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HEp-2 cells persistently infected with respiratory syncytial virus (RSV) are a heterogeneous mixture of viral antigen-positive and -negative variants; however, the mechanism through which viral replication becomes latent remains unclear. In this study, we investigated the potential mechanism by ..., Abstract
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Although IL-12 plays a critical role in priming Th1 and cytotoxic T lymphocyte (CTL) responses, Toll-like receptor (TLR) signaling only induces low amounts of IL-12 in dendritic cells and macrophages, implying the existence of stringent regulatory mechanisms. In this study, we sought to uncover ..., Abstract
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Innate immunity is critical for the control of virus infection and operates to restrict viral susceptibility and direct antiviral immunity for protection from acute or chronic viral-associated diseases including cancer. RIG-I like receptors (RLRs) are cytosolic RNA helicases that function as ..., Abstract
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HBV is the predominant pathogen associated with hepatitis cases in China. Although the HBV replication mechanism has been extensively documented in recent years, the virus entry mechanism remains elusive; in particular, the HBV receptor has yet to be identified. Recently, a research team led by Dr. ..., Abstract
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Ebola virus infection causes severe hemorrhagic fever in human and non-human primates with high mortality. Viral entry/infection is initiated by binding of glycoprotein GP protein on Ebola virion to host cells, followed by fusion of virus-cell membrane also mediated by GP. Using an human ..., Abstract
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Inducing animal viruses to adapt to chicken embryos or chicken embryo fibroblasts (CEF) is a common method to develop attenuated live vaccines with full security. Canine distemper virus (CDV) also does this, but the mechanisms and particular receptors remain unclear. Virus overlay protein blot ..., Abstract
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Herpes simplex viruses (HSV-1 and HSV-2) cause global morbidity and synergistically correlate with HIV infection. HSV exists life-long in a latent form in sensory neurons with intermittent reactivation, in despite of host immune surveillance. While abundant evidence for HSV interfering with innate ..., Abstract
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Heparan sulfate (HS); Herpesviruses; Herpes simplex virus type-1 (HSV-1); 3-O-sulfotransferases; Viral entry, Abstract
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Integrins are members of a ubiquitous membrane receptor family which includes 18 different α subunits and 8 β subunits forming more than 20 α/β heterodimers. Integrins play key functions in vascular endothelial cell and tumour cell adhesion, lymphocyte trafficking, tumor growth and viral ..., Abstract
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In order to express the recombinant protein of SARS-CoV S receptor-binding region and to study its immunogenicity,the gene encoding SARS-CoV S receptor-binding region was cloned to pET32a+ and expressed in E.coli.The expression of the recombinant protein was confirmed by Western blot analysis.The S ..., Abstract
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In this paper, based on the especial interaction among purificated Dengue 2 virus, monoclon-
al antibody against Dengue virus, virus receptor, and Protein-G-Agrose; one non-glyprotein, which molecular weigt is approximately 35kDa, has been identified to be the receptor of Dengue 2 virus on the ..., Abstract
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One ORF of White spot syndrome virus(WSSV)genome has homology with the cytokine
receptor.This ORF contains 2022 nucleotides and codes for 674 amino acids with a theoretical
molecular weight of 76 kDa.Th is putative gene contains one conserved motif of eukaryotic cytokine
receptor ..., Abstract
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In order to construct bicistronic expression vector of RANTES and SDF-l,the ligands of HIV-1 principal coreceptors,RANTES-KDEL were amplified from pCMV-R-K by PCR and ligased with eukaryotic expression vector pCMV-S/K. The construction of pCMV-R-K-S-K was confirmed by enzymatic digestion and ..., Abstract
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Abstract:This research provides the evidence about the identification of haculovirus receptors present
in midgut cell lystes.Rabbit antiserum against purified PDV of SpltM NPV was produced Total midgut
eel1 proteins were prepared with SDS lysis buffer with or wi出OUt ..., Abstract
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The present is aimed at identifying the activation of TRAFs in nasopharyngeal carcinoma
(NPC)ill"oitro The differentia1 expression of TRAF2、TRAF3 was not detected in RNA and protein
1evel,whereas the expression of TRAF1 in HNE2一LM P1 eel1 1ines was much more abundant than that
in ..., Abstract
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