Hello guest, Register  |  Sign In
Special Issues of Virologica Sinica
Current Issue:
Human cytomegalovirus (HCMV) infection is a leading cause of birth defects, primarily affecting the central nervous system and causing its maldevelopment. Hes1, a downstream effector of Notch signaling pathway, plays an essential role on maintaining neural progenitor /stem cells (NPCs) cell fate and fetal brain development. In this issue, Xi-Juan Liu et al. reported the first observation of Hes1 oscillatory expression in human NPCs, and found HCMV infection disrupting the Hes1 rhythm and down-regulates its expression. The cover is adopted from a two-photon fluorescence image of Hes1 staining in NPCs (kindly provided by Xi-Juan Liu and Min-Hua Luo), and further processed with pseudo-color (in teal) at cytosol part. Like Hes1 rhythm, water lily also holds it..., Read More >>
Special Issues:
Home |  Resources |  About Us |  Support |  Contact Us |  Privacy |  Powered by CanSpeed | 
Copyright © 2015 Virologica Sinica. All rights reserved