Virologica Sinica

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A quadrivalent norovirus vaccine based on a chimpanzee adenovirus vector induces potent immunity in mice

Yihua Jiang , Lingjin Sun , Nan Qiao , Xiang Wang , Caihong Zhu , Man Xing , Hui Liu , Ping Zhou , Dongming Zhou

Received: 20 November 2023 Accepted: 08 July 2024

[Abstract] [PDF 2464KB] ScienceDirectESM

Structural and functional insights into the 2'-O-methyltransferase of SARS-CoV-2

Jikai Deng , Feiyu Gong , Yingjian Li , Xue Tan , Xuemei Liu , Shimin Yang , Xianying Chen , Hongyun Wang , Qianyun Liu , Chao Shen , Li Zhou , Yu Chen

Received: 24 November 2023 Accepted: 02 July 2024

[Abstract] [PDF 4446KB] ScienceDirectESM

AIMP2 restricts EV71 replication by recruiting SMURF2 to promote the degradation of 3D polymerase

Junrui Ren , Lei Yu , Qiuhan Zhang , Pengyu Ren , Yumeng Cai , Xueyun Wang , Ke Lan , Shuwen Wu

Received: 19 March 2024 Accepted: 25 June 2024

[Abstract] [PDF 2261KB] ScienceDirectESM

The binding and structural basis of fox ACE2 to RBDs from different sarbecoviruses

Junsen Chen , Junqing Sun , Zepeng Xu , Linjie Li , Xinrui Kang , Chunliang Luo , Qi Wang , Xueyang Guo , Yan Li , Kefang Liu , Ying Wu

Received: 19 March 2024 Accepted: 06 June 2024

[Abstract] [PDF 4069KB] ScienceDirectESM

Detection of HBV DNA integration in plasma cell-free DNA of different HBV diseases utilizing DNA capture strategy

Zerui Yang , Jingyan Zeng , Yueyue Chen , Mengchun Wang , Hongchun Luo , Ai-Long Huang , Haijun Deng , Yuan Hu

Received: 24 January 2024 Accepted: 04 June 2024

[Abstract] [PDF 1718KB] ScienceDirectESM

Pseudorabies virus VHS protein abrogates interferon responses by blocking NF-κB and IRF3 nuclear translocation

Zhenfang Yan , Jiayu Yue , Yaxin Zhang , Zhengyang Hou , Dianyu Li , Yanmei Yang , Xiangrong Li , Adi Idris , Huixia Li , Shasha Li , Jingying Xie , Ruofei Feng

Received: 05 January 2024 Accepted: 23 May 2024

[Abstract] [PDF 4123KB] ScienceDirectESM

Calmodulin-like 5 promotes PEDV replication by regulating late-endosome synthesis and innate immune response

Wen-Jun Tian , Xiu-Zhong Zhang , Jing Wang , Jian-Feng Liu , Fu-Huang Li , Xiao-Jia Wang

Received: 06 December 2023 Accepted: 15 May 2024

[Abstract] [PDF 3964KB] ScienceDirectESM

Design of antiviral AGO2-dependent short hairpin RNAs

Yuanyuan Bie , Jieling Zhang , Jiyao Chen , Yumin Zhang , Muhan Huang , Leike Zhang , Xi Zhou , Yang Qiu

Received: 11 March 2024 Accepted: 06 May 2024

[Abstract] [PDF 2017KB] ScienceDirectESM

RNA viromes of Dermacentor nuttalli ticks reveal a novel uukuvirus in Qīnghăi Province, China

Yaohui Fang , Jun Wang , Jianqing Sun , Zhengyuan Su , Shengyao Chen , Jian Xiao , Jun Ni , Zhihong Hu , Yubang He , Shu Shen , Fei Deng

Received: 17 December 2023 Accepted: 23 April 2024

[Abstract] [PDF 1440KB] ScienceDirectESM

Pseudorabies virus manipulates mitochondrial tryptophanyl-tRNA synthetase 2 for viral replication

Xiu-Qing Li , Meng-Pan Cai , Ming-Yang Wang , Bo-Wen Shi , Guo-Yu Yang , Jiang Wang , Bei-Bei Chu , Sheng-Li Ming

Received: 10 October 2023 Accepted: 11 April 2024

[Abstract] [PDF 2990KB] ScienceDirectESM

Establishment and application of a surrogate model for human Ebola virus disease in BSL-2 laboratory

Wanying Yang , Wujian Li , Wujie Zhou , Shen Wang , Weiqi Wang , Zhenshan Wang , Na Feng , Tiecheng Wang , Ying Xie , Yongkun Zhao , Feihu Yan , Xianzhu Xia

Received: 17 November 2023 Accepted: 22 March 2024

[Abstract] [PDF 6985KB] ScienceDirect

An optimized high-throughput SARS-CoV-2 dual reporter trans-complementation system for antiviral screening in vitro and in vivo

Yingjian Li , Xue Tan , Jikai Deng , Xuemei Liu , Qianyun Liu , Zhen Zhang , Xiaoya Huang , Chao Shen , Ke Xu , Li Zhou , Yu Chen

Received: 04 December 2023 Accepted: 21 March 2024

[Abstract] [PDF 5827KB] ScienceDirectESM

Integration of HiBiT into enteroviruses: A universal tool for advancing enterovirus virology research

Rui Yu , Xiaohong Li , Peng Zhang , Minghao Xu , Jitong Zhao , Jingjing Yan , Chenli Qiu , Jiayi Shu , Shuo Zhang , Miaomiao Kang , Xiaoyan Zhang , Jianqing Xu , Shuye Zhang

Received: 22 November 2023 Accepted: 11 March 2024

[Abstract] [PDF 2883KB] ScienceDirectESM

KIF5B-mediated internalization of FMDV promotes virus infection

Wei Zhang , Fan Yang , Yang Yang , Weijun Cao , Wenhua Shao , Jiali Wang , Mengyao Huang , Zhitong Chen , Xiaoyi Zhao , Weiwei Li , Zixiang Zhu , Haixue Zheng

Received: 21 September 2023 Accepted: 13 March 2024

[Abstract] [PDF 3976KB] ScienceDirectESM

Precore mutation enhances viral replication to facilitate persistent infection especially in HBeAg-negative patients

Guixin Li , Danli Yang , Xin Liu , Ting Zhang , Hui Liu , Jun Zou , Zimeng Xu , Xiangmei Chen , Lizhong Dai , Hongsong Chen , Fengmin Lu

Received: 07 September 2023 Accepted: 11 March 2024

[Abstract] [PDF 3613KB] ScienceDirectESM

Transmission restriction and genomic evolution co-shape the genetic diversity patterns of influenza A virus

Xiao Ding , Jingze Liu , Taijiao Jiang , Aiping Wu

Received: 04 December 2023 Accepted: 22 February 2024

[Abstract] [PDF 2957KB] ScienceDirectESM

C1QTNF5 is a novel attachment factor that facilitates the entry of influenza A virus

Lei Yu , Xinjin Liu , Xiaoqin Wei , Junrui Ren , Xueyun Wang , Shuwen Wu , Ke Lan

Received: 17 October 2023 Accepted: 16 January 2024

[Abstract] [PDF 2320KB] ScienceDirect

RNA barcode segments for SARS-CoV-2 identification from HCoVs and SARSr-CoV-2 lineages

Changqiao You , Shuai Jiang , Yunyun Ding , Shunxing Ye , Xiaoxiao Zou , Hongming Zhang , Zeqi Li , Fenglin Chen , Yongliang Li , Xingyi Ge , Xinhong Guo

Received: 08 April 2023 Accepted: 17 January 2024

[Abstract] [PDF 2494KB] ScienceDirectESM

PABP-driven secondary condensed phase within RSV inclusion bodies activates viral mRNAs for ribosomal recruitment

Qiang Zhang , Hanzhe Ye , Cong Liu , Haiwu Zhou , Mingbin He , Xiaodong Liang , Yu Zhou , Kun Wang , Yali Qin , Zhifei Li , Mingzhou Chen

Received: 18 November 2023 Accepted: 03 December 2023

[Abstract] [PDF 8772KB] ScienceDirectESM

Rapid identification of full-length genome and tracing variations of monkeypox virus in clinical specimens based on mNGS and amplicon sequencing

Changcheng Wu , Ruhan A , Sheng Ye , Fei Ye , Weibang Huo , Roujian Lu , Yue Tang , Jianwei Yang , Xuehong Meng , Yun Tang , Shuang Chen , Li Zhao , Baoying Huang , Zhongxian Zhang , Yuda Chen , Dongfang Li , Wenling Wang , Ke-jia Shan , Jian Lu , Wenjie Tan

Received: 23 September 2023 Accepted: 04 December 2023