YANG Ying-Zhen, GUO Ji, JIN Pei-Yang, PU Shou-Ru, Cheng-Juan-Ru, JIN Ru-Xian, CHEN Hao-Zhu, GONG Jie-Xun and CHEN Ju-Yang. EFFECT OF ASTRAGALUS MEMBRANACEUS (AM) ON COXSACKIE B-2 VIRUS INFECTED RAT BEATING HEART CELLS IN CULTURE[J]. Virologica Sinica, 1986, 1(3).
Citation:
YANG Ying-Zhen, GUO Ji, JIN Pei-Yang, PU Shou-Ru, Cheng-Juan-Ru, JIN Ru-Xian, CHEN Hao-Zhu, GONG Jie-Xun, CHEN Ju-Yang.
EFFECT OF ASTRAGALUS MEMBRANACEUS (AM) ON COXSACKIE B-2 VIRUS INFECTED RAT BEATING HEART CELLS IN CULTURE .VIROLOGICA SINICA, 1986, 1(3)
: 43.
黄芪对培养的搏动大鼠心肌细胞感染Coxsackie B-2病毒的影响
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1.
上海市心血管病研究所
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2.
上海医科大学附属中山医院
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3.
中国科学院上海生物化学研究所
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4.
中国科学院上海生物化学研究所 上海
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摘要
黄芪对Coxsackie B-2病毒感染培养的大鼠心肌细胞所致心肌酶-乳酸脱氢酶、谷草转氨酶的释放、搏动停止、细胞病变、细胞毒性及超微结掏改变等均有明显保护作用。尤其在感染后1—9小时给药保护作用完全。给药后病毒滴度仍能测得,但明显低于病毒对照组。本结果可作为进一步防治急性病毒性心肌炎提供线索。
EFFECT OF ASTRAGALUS MEMBRANACEUS (AM) ON COXSACKIE B-2 VIRUS INFECTED RAT BEATING HEART CELLS IN CULTURE
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1.
Shanghai Institute of Cardiovascnlar Diseases
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2.
Zhong-shan Hospital
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3.
Shanghai Medical University
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4.
Shanghai Shanghai Institute of Biochemistry
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Abstract
The protective effect of Astragalus Membranaceus(AM) on Coxsackie B-2 virus infected newborn rat heart cell cultures was observed. The cardiac enzymes-lactic acid dehydrogenase (LDH) and glutamic oxaloacetic transaminase (SGOT) in infected group were much higher than in those groups of uninfected. AM control, and AM treated 1 hr after inoculation with 100 TCID50 Coxsackie B-2 virus for 2—5 days (p<0.01). The beating percentage began to decrease in infected group at the 2nd day and-no beating was shown 3—...
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References
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Proportional views
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