Detection and Significance of Circulating HBsAg/IgA Immune Complexes in Patients with Hepatitis B

BANG Xuan-Xian; FANG Liang; XIE Tian-Yi; LI Zhao-Rui; LI Jian-Sheng

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February 1990

BANG Xuan-Xian, FANG Liang, XIE Tian-Yi, LI Zhao-Rui and LI Jian-Sheng. Detection and Significance of Circulating HBsAg/IgA Immune Complexes in Patients with Hepatitis B[J]. Virologica Sinica, 1990, 5(1).

Citation: BANG Xuan-Xian, FANG Liang, XIE Tian-Yi, LI Zhao-Rui, LI Jian-Sheng. Detection and Significance of Circulating HBsAg/IgA Immune Complexes in Patients with Hepatitis B .VIROLOGICA SINICA, 1990, 5(1) : 24.

乙型肝炎IgA类HBsAg循环免疫复合物的检测及意义

1.
江西大学生物系微生物学教研室
2.
西安医科大学病毒学研究室
3.
西安市传染病医院
4.
西安市传染病医院南昌

摘要

本文报道用捕捉法ELISA检测各型乙肝IgA型HBsAg循环免疫复合物。结果表明,慢性乙肝IgA型HBsAg循环免疫复合物检出率显著高于急性乙肝;在慢性乙肝中,IgA型HBsAg循环免疫复合物的出现与HBVe系统关系密切,主要存在于HBeAg阳性血清中,并与HBeAg滴度有关。故IgA型HBsAg循环免疫复合物可作为HBV慢性感染的血清诊断标志之一;也可作为反映HBV在增殖并有传播危险的标志之一。
- 酶联免疫吸附试验
- , 乙型病毒性肝炎
- , 循环免疫复合物
- , 免疫球蛋白A
- , 乙型肝炎病毒表面抗原

Detection and Significance of Circulating HBsAg/IgA Immune Complexes in Patients with Hepatitis B

1.
Department of Biology. Jiangxi University
2.
Jiangxi 330047

Abstract

Circulating HBsAg/IgA immune complexes were detected in different groups of hepatitis B patiens by ACCA-ELISA(antibody class capture assay ELISA). The positive rates of chronic hepatitis B were significantly higher than those of acute hepatitis B, The occuranceof circulating HBsAg/IgA immune complexes was closely associated with HBV e system and the titer of HBeAg. These results seem to indicate that the immune response to form circulating HBsAg/IgA immune complexes may be a valuable marker of chronic infec...
- ELISA Hepatitis B Circulating immune complex IgA HBsAg

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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Detection and Significance of Circulating HBsAg/IgA Immune Complexes in Patients with Hepatitis B

1. Department of Biology. Jiangxi University
2. Jiangxi 330047

Abstract: Circulating HBsAg/IgA immune complexes were detected in different groups of hepatitis B patiens by ACCA-ELISA(antibody class capture assay ELISA). The positive rates of chronic hepatitis B were significantly higher than those of acute hepatitis B, The occuranceof circulating HBsAg/IgA immune complexes was closely associated with HBV e system and the titer of HBeAg. These results seem to indicate that the immune response to form circulating HBsAg/IgA immune complexes may be a valuable marker of chronic infec...